A paraganglioma presenting with a giant mediastinal mass: A case report

Ercan GÜNDÜZ, Recep DURSUN, Ahmet ERBEY, Mustafa İÇER, Yılmaz ZENGİN, Cahfer GÜLOĞLU
1.680 284


Paragangliomas are considerably rare and usually benign chromaffin cell tumors originating from sympathetic ganglia outside adrenal medulla. They are usually asymptomatic and detected incidentally. Tumor spread is through both lymphatic and hematogenous route. However, they may cause symptoms when excessively grown. They can be successfully treated with surgery even if they reach a gigantic size when they are diagnosed at an early period and lack metastases. From this perspective, early diagnosis and treatment of them is of great importance. In this study we present a patient presenting to emergency department with dyspnea and diagnosed with a giant paraganglioma in the anterior mediastinum.


Adrenal medulla; dyspnea; mediastinal mass; paraganglioma

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Adsan, Ö., Koşan, M., Seçkin, S., Han, Ö., Kaygısız, O., 2004. Böbrek metanefrik adenomu ve mesane paragangliyomunun birlikteliği: Olgu sunumu. Türk Üroloji Dergisi. 30, 479-481.

Ekici, K., Mayadağlı, A., Karabulut, G.Ş., Özdemir Z., Oruç, A.F, Kayahan, S., Ceylaner, B.B., 2011. Metastatik paragangliom olgusunda tedavi yaklaşımı: Olgu sunumu. J. Kartal TR. 22, 89-93.

Lee, K.Y., Oh,Y.W., Noh, N.J., Lee, Y.J., Yong, H.S., Kang, E.Y., et al. 2006. Extra adrenal paragangliomas of the body: Imaging features: AJR. 187, 492-504.

Rha, S.E., Byun, J.Y., Jung, S.E., Chun, H.J., Lee, H.G., Lee, J.M., 2003. Neurogenic tumors in the abdomen: Tumor types and imaging characteristics. Radiographics. 23, 29-43.

Sobol, S.M., Dailey, J.C., 1990. Familial multiple cervical paragangliomas: Report of a kindred and review of the literature. Otolaryngol Head Neck Surg. 102, 382-390.

Sofikerim, M., Tatlışen, A., Öztürk, F., Tokat, F., 2006. Perivezikal paraganglioma: Olgu sunumu. Türk Üroloji Dergisi. 32, 433-435. Soylu, L., Aydın, S., Alper SM, Atalay F., 2009. Retroperitoneal ekstraadrenal dev paraganglioma: Olgu sunumu. Ulusal Cerrahi Dergisi. 25, 178-1

Tekin, A., Küçükkartallar, T., Vatansev, C., Aksoy, F., 2008. Nadir bir paraganglioma olgusu: Tiroid paraganglioması. Süleymen Demirel Tıp Fakültesi Dergisi. 15, 38-40.